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Principal Software Engineer

Endpoint Clinical · Remote US

Extracted from the posting

Base
$160,000 – $170,000
Remote
Full-time, remote within the United States
Stack
TypeScript, React, Node.js, SQL

Principal individual contributor engineer for Bluefin, Endpoint's clinical supply forecasting platform, with a Rust simulation engine compiled to WebAssembly. Work spans UX/UI, TypeScript/React/Node.js frontend and backend, and SQL data modeling, including feature delivery, refactors, and mentoring engineers. Requires 12+ years of engineering experience.

About Us:


Endpoint is an interactive response technology (IRT®) systems and solutions provider that supports the life sciences industry. Since 2009, we have been working with a single vision in mind, to help sponsors and pharmaceutical companies achieve clinical trial success. Our solutions, realized through the proprietary PULSE® platform, have proven to maximize the supply chain, minimize operational costs, and ensure timely and accurate patient dosing. Endpoint is headquartered in Raleigh-Durham, North Carolina with offices across the United States, Europe, and Asia.


About Bluefin 

Bluefin is Endpoint Clinical's clinical supply forecasting and planning platform. We help our users explore supply scenarios, anticipate risk, and make informed decisions through sub-second simulations of complex supply chains. Our Rust simulation engine runs directly in the browser through WebAssembly. 

We believe powerful software should be straightforward to use. We design workflows that don't require a manual and take pride in quickly bringing value to our users. 

The Role 

We're hiring a hands-on principal engineer to help shape Bluefin, its engineering team, and engineering practices across Endpoint. You'll work across UX/UI design, frontend and backend development, and the simulation engine, connecting an intuitive user experience with complex forecasting behavior. 

Alongside our technical lead, you'll mentor engineers, challenge established approaches and grow toward independent technical ownership of the platform. This is an individual contributor role with broad influence and substantial hands-on work. 

Responsibilities

    Experience

    • 12+ years of engineering excellence

    Education

    • Bachelors degree or higher in Computer Science or other relevant field preferred

    Required Skills

      What You'll Learn

        Compensation

          Endpoint Clinical does not accept unsolicited resumes from search firms or any other third parties. Any unsolicited resume sent to Endpoint Clinical will be considered Endpoint Clinical property, and Endpoint Clinical will not pay a fee should it hire the subject of any unsolicited resume.


          Endpoint Clinical is an equal opportunities employer AA/M/F/Veteran/Disability.    

           

          Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment, qualified applicants with arrest and conviction records.

          #LI-MT

          Compensation: USD 160,000 – 170,000 per year salary

          Technologies

          TypeScriptReactNode.jsSQLRustHTMLCSSWebAssemblyTailwind CSSGoC++Java
          Endpoint Clinical
          Endpoint Clinical

          Job details

          TypeFull-time
          Work ModeRemote
          LevelSenior
          LocationRemote US
          Salary$160,000 - $170,000
          PostedNov 06, 2026
          Apply Now

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